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Research Articles

Randomized Controlled Trial

Patiromer utility as an adjunct treatment in patients needing urgent hyperkalaemia management (PLATINUM): a randomised controlled trial in the emergency department.

Patiromer Shows No Added Benefit Over Placebo for Acute Hyperkalaemia in Emergency Settings — In a randomised, double-blind, placebo-controlled trial across 16 US emergency departments, patiromer added to standard combination therapy produced no statistically significant improvement in net clinical benefit or potassium reduction at 6 hours compared with placebo (-0.

Mar 4, 2026 · BMJ Open · Metabolism
88
Randomized Controlled Trial

Coronary atherosclerotic plaque intervention with Tongxinluo capsule (TXL-CAP): a multicenter, randomized, double-blind and placebo-controlled study.

Tongxinluo Capsule Increases Coronary Plaque Fibrous Cap Thickness Over 12 Months — In patients with acute coronary syndrome, adding Tongxinluo capsule to standard statin therapy produced a meaningfully greater increase in minimum fibrous cap thickness compared to placebo at 12 months (115.

Mar 4, 2026 · Signal Transduct Target Ther · Cardiology
91